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Publications

Imaging Mass Spectrometry:

  1. Brian Malys, Kevin G. Owens*, “Improving the Analyte Ion Signal in Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry via Electrospray Deposition by Enhancing Incorporation of the Analyte in the Matrix”, Rapid Commun. Mass Spectrom., 31(9) 804-12, 2017, http://dx.doi.org/10.1002/rcm.7848

  2. Brian Malys, Michelle Piotrowski, Kevin G. Owens*, “Diagnosing and Correcting Mass Accuracy and Signal Intensity Error Due to Initial Ion Position Variations in a MALDI TOFMS”, J. Amer. Soc. Mass Spectrom., 29(2), 422–434, 2018, DOI: http://dx.doi.org//10.1007/s13361-017-1845-2.

  3. Michelle Piotrowski, Brian Malys, Kevin G. Owens*, “A Method for Defining Initial Ion Position in a MALDI TOFMS by Analysis of the Laser Image on the Sample Surface”, J. Amer. Soc. Mass Spectrom., 30(3), 489-500, 2019, DOI: http://dx.doi.org/10.1007/s13361-018-2107-7.

 

Micro-Organism Identification by Mass Spectrometry:

  1. Elsa Gorre, Cathy Muste, Kevin G. Owens*, “Introducing a Cell-Free Approach for the Identification of Brewing Yeast Strains using MALDI TOF MS”, J. Amer. Soc. Mass Spectrom., 29(11), 2248-59, 2018, http://dx.doi.org//10.1007/s13361-018-2031-x.

  2. Cathy Muste, Kevin G. Owens*, “Cell-Free Identification of Strains by Analysis of Supernatant using LC/MS”, J. Amer. Soc. Mass Spectrom., 29(11), 2260-7, 2018, http://dx.doi.org/10.1007/s13361-018-2046-3.

 

Principles of the Matrix-Assisted Laser Desorption Ionization (MALDI) Technique:

  1. Yansan Xiong, Kevin G. Owens, Dane E. Karr, Paul O. Danis* "A Novel Cationization Reagent for the Analysis of Hydrocarbon Polymers by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry", Rapid Commun. Mass Spectrom., 10(7), 862-9, 1996. DOI: http://dx.doi.org/10.1002/(SICI)1097-0231(199605)10:7%3C862::AID-RCM578%3E3.0.CO;2-X

  2. Russell R. Hensel, Richard C. King, Kevin G. Owens*, “Electrospray Sample Preparation for Improved Quantitation in Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry", Rapid Commun. Mass Spectrom., 11(16), 1785-93, 1997. DOI: http://dx.doi.org/10.1002/(SICI)1097-0231(19971030)11:16%3C1785::AID-RCM78%3E3.0.CO;2-Q

  3. Scott D. Hanton*, Paula A. Cornelio Clark, Kevin G. Owens, “Investigations of MALD/I Sample Preparation by ToF-SIMS”, J. Amer. Soc. Mass Spectrom., 10(2), 104-111, 1999. DOI: http://dx.doi.org/10.1016/S1044-0305(98)00135-4

  4. Stephen F. Macha, Patrick A. Limbauch*, Scott D. Hanton, Kevin G. Owens, “Matrix-Silver Cluster Interferences in the Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) of Non-Polar Polymers”, J. Amer. Soc. Mass Spectrom., 12(6), 732-43, 2001. DOI: http://dx.doi.org/10.1016/S1044-0305(01)00225-2

  5. Colin S. Creaser*, James C. Reynolds, Andrew J. Hoteling, William F. Nichols, Kevin G. Owens, “Atmospheric Pressure-Matrix Assisted Laser Desorption Ion Trap Mass Spectrometry of Synthetic Polymers: A Comparison with MADLI-TOF”, European Journal of Mass Spectrometry, 9(1), 33-44, 2003. DOI: http://dx.doi.org/10.1255/ejms.528

  6. Andrew J. Hoteling, Kenji Kawaoka, Mary C. Goodberlet, Wan-Mo Yu, Kevin G. Owens*, “Optimization of MALD/I TOF CID – MS/MS of Poly(Ethylene Glycol)”, Rapid Commun. Mass Spectrom., 17, 1671-6, 2003. DOI: http://dx.doi.org/10.1002/rcm.1084

  7. Scott D. Hanton*, Kevin G. Owens, William Blair*, Ingrid Z. Hyder, James R Stets, Charles M. Guttman, and Anthony Giuseppetti, “Investigations of Electrospray Sample Deposition for Polymer MALDI”, J. Amer. Soc. Mass Spectrom., 15(2), 168-179, 2004. DOI: http://doi.org/10.1016/j.jasms.2003.09.012

  8. Andrew J. Hoteling and Kevin G. Owens*, “Improved PSD and CID on a MALDI/TOFMS J. Amer. Soc. Mass Spectrom., 15(4), 523-35, 2004. DOI: http://dx.doi.org/10.1016/j.jasms.2003.12.004

  9. Andrew J. Hoteling, William J. Erb, Robert J. Tyson, III and Kevin G. Owens*, “Exploring the Importance of the Relative Solubility of Matrix and Analyte in MALDI Sample Preparation using HPLC”, 76(17), 5157-64, 2004. DOI: http://dx.doi.org/10.1021/ac049566m

  10. Scott D. Hanton*, David A. Parees, Kevin G. Owens, “MALDI PSD of Low Molecular Weight Ethoxylated Polymers, Intl. J. Mass Spectrom., 238(3), 257-264, 2004. DOI: http://dx.doi.org/10.1016/j.ijms.2004.09.028

  11. Andrew J. Hoteling, Thomas H. Mourey, Kevin G. Owens*, “The Importance of Solubility in the Sample Preparation of Poly(Ethylene Terephthalate) for MALD/I TOFMS”, Analytical Chemistry, 77(3), 750-756, 2005. DOI: http://dx.doi.org/10.1021/ac048525n

  12. Thomas H. Mourey*, Andrew J. Hoteling, Stephen T. Balke, Kevin G. Owens, “Molar Mass Distributions of Polymers from SEC and MALDI-TOF MS: Methods for Comparison”, Journal of Applied Polymer Science, 97, 627-639, 2005. DOI: http://dx.doi.org/10.1002/app.21803

  13. Scott D. Hanton*, Kevin G. Owens, Cynthia Chavez-Eng, Anne-Mette Hoberg, and Peter J. Derrick, “Updating Evidence for Cationization of Polymers in the Gas Phase during Matrix-Assisted Laser Desorption/Ionization”, European Journal of Mass Spectrometry, 11(1), 23-29, 2005. DOI: http://dx.doi.org/10.1255/ejms.715

  14. Scott D. Hanton* and Kevin G. Owens, “Using MESIMS to Analyze Polymer MALDI Matrix Solubility”, J. Amer. Soc. Mass Spectrom., 16, 1172-1180, 2005. DOI: http://dx.doi.org/10.1016/j.jasms.2005.03.013

  15. William J. Erb, Kevin G. Owens*, Scott D. Hanton, “A Study of Gas Phase Cationization in Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry”, Rapid Commun. Mass Spectrom., 20(14), 2165-9, 2006. DOI: http://dx.doi.org/10.1002/rcm.2568

  16. William J. Erb and Kevin G. Owens*, “Development of a Dual-Spray Electrospray Deposition System”, Rapid Commun. Mass Spectrom., 22(8), 1168-1174, 2008. DOI: http://dx.doi.org/10.1002/rcm.3492

  17. April Holcomb and Kevin G. Owens*, “Optimization of a Modified Aerospray Deposition Device for the Preparation of Samples for Quantitative Analysis by MALDI TOFMS”, Analytical Chimica Acta, 658, 49-55, 2010. DOI: http://dx.doi.org/10.1016/j.aca.2009.10.060

  18. Renata Szyszka, Scott D. Hanton, Diane M. Henning, Kevin G. Owens*, “Quantitation of PEG Contaminants in Ethoxylated Surfactant Samples by MALDI TOFMS using Standard Additions and Internal Standards Methods”, J. Amer. Soc. Mass Spectrom., 22(4), 633-40, 2011. DOI: https://doi.org/10.1007/s13361-010-0065-9

  19. Elsa Gorre, Kevin G. Owens*, “Microscale Solubility Measurements of MALDI Matrices Using ATR FT-IR Absorption Spectroscopy Coupled with PLS Analysis”, Applied Spectroscopy, 70(11), 1831-41, 2016, http://dx.doi.org/10.1177/0003702816647730.

  20. Andrew J. Hoteling, Michelle Piotrowski, Kevin G. Owens*, “The Cationization of Synthetic Polymers in MALDI TOFMS: Investigations of the Salt-to-Analyte Ratio”, Rapid Commun. Mass Spectrom., 34(S2), e8630, 2020, http://dx.doi.org/10.1002/rcm.8630

 

Book Chapters:

  1. Scott D. Hanton* and Kevin G. Owens, “MALDI MS Applications for Industrial Polymers”, in Liang Li, ed., MALDI Mass Spectrometry for Synthetic Polymer Analysis, New York: John Wiley & Sons, Inc., 2010.

  2. Kevin G. Owens* and Scott D. Hanton, “Conventional MALDI Sample Preparation”, in Liang Li, ed., MALDI Mass Spectrometry for Synthetic Polymer Analysis, New York: John Wiley & Sons, Inc., 2010.

  3. Scott D. Hanton* and Kevin G. Owens, “Polymer MALDI Sample Preparation", in Christopher Barner‐Kowollik, Jana Falkenhagen, Till Gründling, Steffen Weidner, eds., Mass Spectrometry in Polymer Chemistry, Wiley-VCH Publishers, 2012.

 

Patents & Applications:

  1. Kevin G. Owens, Jonathan Haulenbeek, "System and Method for Controlled Electrospray Deposition", U.S. Provisional Patent Application No. 61/348,080, filed May 25, 2010 by Drexel University; International Patent Application PCT/US2011/037918, August 1, 2011 (DREX-1125), declined to pursue, 11/12.

  2. Kevin G. Owens, Michelle Piotrowski, Brian Malys, "Method for Determining Flight Axis Initial Ion Position in a Time-of-Flight Mass Spectrometer", submitted to Drexel Office of Technology Commercialization 11/21/17, (DREX-17-2068), declined to pursue, 2/18.

 

Time-of-Flight Mass Spectrometry:

  1. R.B. Opsal, K.G. Owens, J.P. Reilly*, "Resolution in the Time-of-Flight Mass Spectrometer", Anal. Chem., 57(9), 1884-9, 1985. DOI: http://dx.doi.org/10.1021/ac00286a020.

 

Patents & Applications:

  1. Kevin G. Owens, Richard C. King III, Bruce N. LaPrade, H. Carl Boyer, Neil E. White, George Grubner, Stavre Vesovski, John Leason, Dennis Kosakowski, “Bipolar Time of Flight Detector”. U.S. Provisional Application Serial No. 60/189,894, filed March 16, 2000 by Burle Electro-Optics, Inc.

  2. Kevin G. Owens, Richard C. King, Bruce N. LaPrade, “Bipolar Time-of-Flight Detector, Cartridge, and Detection Method”, US patent # 6,828,729, issued December 7, 2004. U.S. Patent Application, filed March 16, 2001 by Burle Electro-Optics, Inc.

 

Chemometrics/Correlation Analysis Applied to MS

  1. K.G. Owens*, "Application of Correlation Analysis Techniques to Mass Spectral Data", Applied Spectroscopy Reviews, 27(1), 1-49, 1992. DOI: http://dx.doi.org/10.1080/05704929208018268

  2. Carmen L. Fernandez-Metzler*, Thomas A. Baillie, Kevin G. Owens, Richard C. King, "Rapid LC-MS/MS Based Screening Procedures for Studies of the Biotransformation of Drug Candidates", Drug Metabolism and Disposition, 27(1), 32-40, 1999.

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Patents & Applications:

  1. Kevin G. Owens, “Automated Method for Mass Spectral Data Analysis”, U.S. Provisional Application Serial No. 60/157,714, filed October 5, 1999 by Drexel University, declined to pursue.

 

Analysis of C60 and C70 Fullerenes by MALDI:

  1. A.B. Smith, III*, R.M. Strongin, L. Brard, G.T. Furst, W.J. Romanow, K.G. Owens, R.C. King, “1,2-Methanobuckminsterfullerene (C61H2), The Parent Fullerene Cyclopropane: Synthesis and Structure”, J. Amer. Chem. Soc., 115, 5829-30, 1993. DOI: http://dx.doi.org/10.1021/ja00066a063

  2. Amos B. Smith, III*, Robert M. Strongin, Laurent Brard, GeorgeT. Furst, William J. Romanow, Kevin G. Owens, Robert J. Goldschmidt, “C71H2 Cyclopropanes and Annulenes: Synthesis and Characterization”, J. Chem. Soc., Chem. Commun, 1994, 2187-8. DOI: http://dx.doi.org/10.1039/c39940002187

  3. Amos B. Smith, III*, Robert M. Strongin, Laurent Brard, GeorgeT. Furst, William J. Romanow, Kevin G. Owens*, Robert J. Goldschmidt, R.C. King, “Synthesis of Prototypical Fullerene Cyclopropanes and Annulenes.Isomer Differentiation via NMR and UV Spectroscopy”, Journal of the American Chemical Society, , 5492-5502, 1995. DOI: http://dx.doi.org/10.1021/ja00125a009

  4. Amos B. Smith, III*, Robert M. Strongin, Laurent Brard, GeorgeT. Furst, Joshua H. Atkins, William J. Romanow, Martin Saunders*, Hugo A. Jiminez-Vazquez, Kevin G. Owens, Robert J. Goldschmidt, “Synthesis and Characterization of the First C70O Epoxides. Utilization of 3He NMR in Analysis of Fullerene Derivatives”, J. Organic Chem., 61(6), 1904-5, 1996. DOI: http://dx.doi.org/10.1021/jo960104l

 

Combustion Analysis/CEMOR (Cavity Enhanced Magneto-Optic Rotation):

  1. Shang J. Tsay, Kevin G. Owens*, Kenneth W. Aniolek, David L. Miller, Nicholas P. Cernansky, “Detection of CN using Degenerate Four-Wave Mixing", Optics Letters, (16), 1725-8, 1995. DOI: http://dx.doi.org/10.1364/OL.20.001725

  2. Kenneth W. Aniolek, David L. Miller, Nicholas P. Cernansky, Kevin G. Owens*, “Generation of 1.30-1.55 mm Tunable Radiation from First Stokes Raman Shifting in Hydrogen", Applied Spectroscopy, 51(6), 820-6, 1997. DOI: http://dx.doi.org/10.1366/0003702971941098

  3. M. Emig, D. L. Miller, R. I. Billmers*, N. P. Cernansky, K. G. Owens, “Cavity Enhanced Magneto-Optic Rotation: A Sensitive and Selective Technique for Detection of Paramagnetic Species”, Chemical and Physical Processes in Combustion, 428-431, 2001.

  4. Mary Emig, Richard I. Billmers*, Kevin G. Owens, Nicholas P. Cernansky, David L. Miller, “Sensitive and Selective Detection of Paramagnetic Species using Cavity Enhanced Magneto-Optic Rotation”, Applied Spectroscopy, 56(7), 863-8, 2002. DOI: http://dx.doi.org/10.1366/000370202760171536.

  5. David B. Lenhert, David L. Miller, Nicholas P. Cernansky, Kevin G. Owens, “The Oxidation of a Gasoline Surrogate in the Negative Temperature Coefficient Region”, Combustion and Flame, 156(3), 549-564, 2009. DOI: http://dx.doi.org/10.1016/j.combustflame.2008.11.022

 

Patents & Applications:

  1. Richard I. Billmers, Mary Emig, Nicholas P. Cernansky, David L. Miller, Kevin G. Owens, Frank Narducci, “Cavity-Enhanced Magneto-Optic Rotation Spectroscopy and Uses Thereof”, U.S. Provisional Application Serial No. 60/379,334, filed May 9, 2002 by Drexel University.

 

Environmental Analysis:

  1. Timothy M. Laumakis, Joseph P. Martin, Sibel Pamucku, Kevin Owens, “Adsorption of Lead in Fly Ash Subgrades for Waste Disposal Facilities”, Innovative Technologies for Site Remediation and Hazardous Waste Management, Proceedings of the National Conference, Pittsburgh, July 23-26, 1995, p. 528-535, 1995.

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Computerized Experimentation:

  1. Jean-Claude Bradley*, Khalid Baig Mirza, Tom Osborne, Antony Williams, Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling”, Journal of Visualized Experiments (JOVE), (21), 2008. DOI: http://dx.doi.org/10.3791/942.

 

Supersonic Jet Spectroscopy/Laser Ionization Mass Spectrometry:

  1. K.G. Owens, J.P. Reilly*, "Probing Argon-Benzene van der Waals Molecules and Isotopically Substituted Benzene with Laser Ionization Mass Spectrometry", J. Opt. Soc. Am. B, 2, 1589-93, 1985. DOI: http://dx.doi.org/10.1364/JOSAB.2.001589

  2. R.B. Opsal, K.G. Owens, J.P. Reilly*, “Chromatographic Effluent Detection with Laser Ionization Mass-Spectrometry”, Journal of the Optical Society of America A-Optics Image Science and Vision, 2(13), P69, 1985.

  3. E. Sekreta, K.G. Owens, J.P. Reilly*, "Intensity-Dependent Laser Ionization Experiments Involving the 1B1u State of Benzene", Chem. Phys. Lett., 132, 450-5, 1986. DOI: http://dx.doi.org/10.1016/0009-2614(86)80644-3.

  4. E. Sekreta, K. Owens, A. Engel, J.P. Reilly*, "Applications of Laser Ionization Spectroscopy", Spectrochim. Acta, Part B, 43b, 679-86, 1988. DOI: http://dx.doi.org/10.1016/0584-8547(88)80090-9.

  5. Z.Q. Zhao, C.S. Parmenter, D.B. Moss, A.J. Bradley, A.E.W. Knight*, K.G. Owens, "p-Fluorotoluene 1. Methyl (CH3 and CD3) Internal Rotation in the S1 and S0 States", J. Chemical Physics, 96(9), 6362-77, 1992. DOI: http://dx.doi.org/10.1063/1.462631

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Statistical Analysis:

  1. K.G. Owens, C.F. Bauer*, C.L. Grant, "Effects of Analytical Calibration Models on Detection Limit Estimates", in L.A. Currie, ed., Detection in Analytical Chemistry: Importance, Theory & Practice, ACS Symposium Series #361, 1988.

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Note that * indicates corresponding author

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